I recently got this error while i was trying to simply compile my orchestration projet so what i’ve done is i tried to change the project target, plateforme, and i got again and again the same error even with an empty new orchestration.

Error 2The “XLangTask” task failed unexpectedly. System.Runtime.InteropServices.COMException (0x80040154): Retrieving the COM class factory for component with CLSID {1BBA9F19-D4CC-34AA-918C-44FEF11E8274} failed due to the following error: 80040154 Class not registered (Exception from HRESULT: 0x80040154 (REGDB_E_CLASSNOTREG)). at Microsoft.VisualStudio.BizTalkProject.Compiler.XLangCompiler.Compile (BizTalkBuildSnapshot buildSnapshot, IEnumerable1 orchestrationFilesToCompile, String switches, String outputPath, List1& generatedCodeFiles) at Microsoft.VisualStudio.BizTalkProject.BuildTasks.XLangTask.Execute() at Microsoft.Build.BackEnd.TaskExecutionHost.Microsoft.Build.BackEnd.ITaskExecutionHost.Execute() at Microsoft.Build.BackEnd.TaskBuilder.ExecuteInstantiatedTask(ITaskExecutionHost taskExecutionHost, TaskLoggingContext taskLoggingContext, TaskHost taskHost, ItemBucket bucket, TaskExecutionMode howToExecuteTask, Boolean& taskResult) JMB.Ocean.Common.BatchTransfer.Orchestrations

So i decided to repair BizTalk Server on my developement machine and it worked ! Hope you find this helpful and win some time